Replens MD 6 Single Pre-filled Applicators Longer Lasting Vaginal Moisturiser For Vaginal Health and Moisture beyond the Menopause Non-Hormonal Oestrogen Free Lasts Up to 3 Days per Application . Soothing- immediate relief from Vaginal Dryness Itching Irritation Discomfort Vaginal dryness (Vaginal Atrophy) is the result of the natural ageing process. It not only affects lovemaking- but often leads to itching- irritation and discomfort. These common problems are caused by lack of natural moisture which originates inside the vagina. Replens MD replenishes this essential moisture.